STRADB anticorps (C-Term)

N° du produit ABIN8112916

Cet anticorps Lapin Polyclonal détecte spécifiquement STRADB dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour STRADB anticorps (C-Term) (ABIN8112916)

Antigène: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STRADB est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-STRADB anticorps

Épitope: C-Term

Fonction: STRADB Antibody - C-terminal region

Séquence: GTHTVNSDRL HTPSSKTFSP AFFSLVQLCL QQDPEKRPSA SSLLSHVFFK

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human STRAB

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49234-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur STRADB

Antigène: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Autre désignation: STRADB

Sujet:

Background Information: This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: STE20-related kinase adaptor beta

Alternative Symbols: PAPK, ILPIP, ILPIPA, ALS2CR2, CALS-21, PRO1038

Protein Name: STE20-related kinase adapter protein beta

Poids moléculaire: 41kDa

ID gène: 55437

UniProt: Q9C0K7

Pathways: AMPK Signaling