SMYD3 anticorps (AA 101-200) (FITC)

N° du produit ABIN760593

Cet anticorps anti-SMYD3 est un anticorps Lapin Polyclonal détectant SMYD3 dans WB, IF (cc) et IF (p). Adapté pour Humain.

Aperçu rapide pour SMYD3 anticorps (AA 101-200) (FITC) (ABIN760593)

Antigène: SMYD3 (SET and MYND Domain Containing 3 (SMYD3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMYD3 est conjugé à/à la FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-SMYD3 anticorps (FITC)

Épitope: AA 101-200

Réactivité croisée: Humain

Homologie: Mouse,Rat,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SMYD3

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SMYD3

Antigène: SMYD3 (SET and MYND Domain Containing 3 (SMYD3))

Autre désignation: SMYD3

Sujet:

Synonyms: SET and MYND domain containing 3, SET and MYND domain containing protein 3, SMYD 3, SMYD3 protein, Zinc finger MYND domain containing 1, Zinc finger MYND domain containing protein 1, Zinc finger protein subfamily 3A MYND domain containing 1, ZMYND 1, ZMYND1, ZNFN3A1, SMYD3_HUMAN.

Background: SMYD3 is a gene that is over-expressed in the majority of colorectal carcinomas and hepatocellular carcinomas. SMYD3 forms a complex with RNA polymerase II through an interaction with the RNA helicase HELZ and transactivates a set of genes that included oncogenes, homeobox genes and genes associated with cell-cycle regulation. SMYD3 binds to a motif, 5'-CCCTCC-3', present in the promoter region of downstream genes such as Nkx2.8. The SET domain of SMYD3 shows histone H3-lysine 4 (H3-K4)-specific methyltransferase activity, which is enhanced in the presence of the heat-shock protein HSP90A.

ID gène: 64754