STXBP2 anticorps
Aperçu rapide pour STXBP2 anticorps (ABIN8113314)
Antigène
Voir toutes STXBP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- STXBP2 Antibody
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Séquence
- CMKHFKGSVE KLCSVEQDLA MGSDAEGEKI KDSMKLIVPV LLDAAVPAYD
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Homologie
- Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the following sequence CMKHFKGSVEKLCSVEQDLAMGSDAEGEKIKDSMKLIVPVLLDAAVPAYD
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64422-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- STXBP2 (Syntaxin Binding Protein 2 (STXBP2))
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Autre désignation
- STXBP2
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Sujet
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Background Information: This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Gene Name: syntaxin binding protein 2
Alternative Symbols: FHL5, UNC18B, Hunc18b, UNC18-2, pp10122, MUNC18-2
Protein Name: Syntaxin-binding protein 2
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Poids moléculaire
- 66 kDa
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ID gène
- 6813
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NCBI Accession
- NP_008880
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UniProt
- Q15833
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
Antigène
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