AMACR anticorps (AA 300-382)

N° du produit ABIN8119690

Cet anticorps anti-AMACR Monoclonal Souris (Clone AB1490) (ABIN8119690) détecte spécifiquement AMACR dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour AMACR anticorps (AA 300-382) (ABIN8119690)

Antigène: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AMACR est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: AB1490

Détail du produit anti-AMACR anticorps

Épitope: AA 300-382

Fonction: AMACR Mouse mAb (Ready to Use)

Specificité: The antibody can specifically recognize human AMACR protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogène: A synthetic peptide corresponding to the amino acid region 300 - 382 of the human AMACR protein.

Isotype: IgG

Information d'application

Indications d'application: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze

Stock: 4 °C

Stockage commentaire: Store at 4°C. Avoid freeze.

Détails sur AMACR

Antigène: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Autre désignation: AMACR

Sujet:

Synonyms: 2 arylpropionyl CoA epimerase, 2 methylacyl CoA racemase, 2-methylacyl-CoA racemase, Alpha methylacyl CoA racemase, Alpha methylacyl Coenzyme A racemase, Alpha methylacyl-CoA racemase deficiency, included, Alpha-methylacyl-CoA racemase, Amacr, AMACR deficiency, included, AMACR_HUMAN, CBAS4, Da1-8, EC 5. 1. 99. 4, Macr1, Methylacyl CoA racemase alpha, RACE, RM

Background: AMACR is an α Formyl COA racemase localized in peroxisomes and mitochondria . It is an enzyme involved in biosynthesis of bile acid and β- oxidation of branched- chain fatty acids. It is expressed in the epithelium and salivary gland of proximal convoluted tubules of pancreas, liver and kidney, and moderately in paraurethral glands. The expression in prostate cancer is higher than that in benign prostate tissue. In the study of prostate cancer, it is often used in combination with PSA, p63, 34 β E12 and other antibodies.

Gene Name: AMACR

Protein Name: AMACR

ID gène: 23600

UniProt: Q9UHK6

Pathways: Monocarboxylic Acid Catabolic Process