AMACR anticorps (AA 300-382)
Aperçu rapide pour AMACR anticorps (AA 300-382) (ABIN8119692)
Antigène
Voir toutes AMACR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 300-382
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Fonction
- AMACR mouse mAb
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Specificité
- The antibody can specifically recognize human AMACR protein. In western blotting of Hela and LnCap cell lysates, the antibody can label a 42 kDa band corresponding to AMACR.
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Purification
- The antibody was purified by protein G affinity chromatography.
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Immunogène
- A synthetic peptide corresponding to the amino acid region 300 - 382 of the human AMACR protein.
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Isotype
- IgG
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Indications d'application
- IHC, 1:100-1:500 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at-20°C. Avoid freeze / thaw cycles.
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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Autre désignation
- AMACR
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Sujet
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Synonyms: 2 arylpropionyl CoA epimerase, 2 methylacyl CoA racemase, 2-methylacyl-CoA racemase, Alpha methylacyl CoA racemase, Alpha methylacyl Coenzyme A racemase, Alpha methylacyl-CoA racemase deficiency, included, Alpha-methylacyl-CoA racemase, Amacr, AMACR deficiency, included, AMACR_HUMAN, CBAS4, Da1-8, EC 5. 1. 99. 4, Macr1, Methylacyl CoA racemase alpha, RACE, RM
Background: AMACR is an α Formyl COA racemase localized in peroxisomes and mitochondria . It is an enzyme involved in biosynthesis of bile acid and β-oxidation of branched-chain fatty acids. It is expressed in the epithelium and salivary gland of proximal convoluted tubules of pancreas, liver and kidney, and moderately in paraurethral glands. The expression in prostate cancer is higher than that in benign prostate tissue. In the study of prostate cancer, it is often used in combination with PSA, p63, 34 β E12 and other antibodies.
Gene Name: AMACR
Protein Name: AMACR
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ID gène
- 23600
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UniProt
- Q9UHK6
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Pathways
- Monocarboxylic Acid Catabolic Process
Antigène
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