alpha-SMA anticorps

N° du produit ABIN8119694

Cet anticorps Lapin Polyclonal détecte spécifiquement alpha-SMA dans WB, ELISA, IHC et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour alpha-SMA anticorps (ABIN8119694)

Antigène: alpha-SMA

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit

Fonction: α-SMA Antibody

Specificité: α-SMA Polyclonal Antibody detects endogenous levels of α-SMA protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human alpha-SMA.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détail du antigène

Antigène: alpha-SMA

Sujet:

Synonyms: ACTA1, ACTA, Actin, alpha skeletal muscle, Alpha-actin-1, ACTA2, ACTSA, ACTVS, GIG46, Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, ACTC1, ACTC, Actin, alpha cardiac muscle 1, Alpha-cardiac actinACTA1, ACTA, Actin, alpha skeletal muscle, Alpha-actin-1, ACTA2, ACTSA, ACTVS, GIG46, Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, ACTC1, ACTC, Actin, alpha cardiac muscle 1, Alpha-cardiac actin

Background: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008],

Gene Name: ACTA1/ACTA2/ACTC1

Protein Name: Actin alpha skeletal muscle/Actin aortic smooth muscle/Actin alpha cardiac muscle 1

ID gène: 59

UniProt: P68133