Amphiphysin anticorps

N° du produit ABIN8119704

L’anticorps anti-Amphiphysin Polyclonal Lapin est utilisé pour la détection de Amphiphysin dans des échantillons de Souris et Rat. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour Amphiphysin anticorps (ABIN8119704)

Antigène: Amphiphysin (AMPH)

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Amphiphysin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Amphiphysin anticorps

Fonction: Amphiphysin II Antibody

Specificité: Amphiphysin II Polyclonal Antibody detects endogenous levels of Amphiphysin II protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human Amphiphysin II.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Amphiphysin

Antigène: Amphiphysin (AMPH)

Autre désignation: Amphiphysin II

Sujet:

Synonyms: BIN1, AMPHL, Myc box-dependent-interacting protein 1, Amphiphysin II, Amphiphysin-like protein, Box-dependent myc-interacting protein 1, Bridging integrator 1

Background: This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq, Mar 2016],

Gene Name: BIN1

Protein Name: Myc box-dependent-interacting protein 1

ID gène: 274

UniProt: O00499