ALS2 anticorps (AA 390-470)

N° du produit ABIN8119717

Cet anticorps anti-ALS2 Polyclonal Lapin (ABIN8119717) détecte spécifiquement ALS2 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ALS2 anticorps (AA 390-470) (ABIN8119717)

Antigène: ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALS2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ALS2 anticorps

Épitope: AA 390-470

Fonction: ALS2 Antibody

Specificité: ALS2 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human protein . at AA range: 390-470

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur ALS2

Antigène: ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))

Autre désignation: ALS2

Sujet:

Background: The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],

Gene Name: ALS2 ALS2CR6 KIAA1563

Protein Name: Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein)

ID gène: 57679

UniProt: Q96Q42

Pathways: Skeletal Muscle Fiber Development