ACE2 anticorps (AA 425-475)

N° du produit ABIN8119736

Cet anticorps Lapin Polyclonal détecte spécifiquement ACE2 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ACE2 anticorps (AA 425-475) (ABIN8119736)

Antigène: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACE2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ACE2 anticorps

Épitope: AA 425-475

Fonction: ACE2 Antibody

Specificité: This antibody detects endogenous levels of ACE2 at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human ACE2 AA range: 425-475

Isotype: IgG

Information d'application

Indications d'application: IHC1:50-200 ,WB 1:1000-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur ACE2

Antigène: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Autre désignation: ACE2

Sujet:

Synonyms: Angiotensin-converting enzyme 2 (EC 3.4.17.23) (ACE-related carboxypeptidase) (Angiotensin-converting enzyme homolog) (ACEH) (Metalloprotease MPROT15) [Cleaved into: Processed angiotensin-converting enzyme 2]

Background: angiotensin I converting enzyme 2(ACE2) Homo sapiensThe protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.

Gene Name: ACE2 UNQ868/PRO1885

Protein Name: ACE2

ID gène: 59272

UniProt: Q9BYF1

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour