Bestrophin 1 anticorps (AA 161-211)

N° du produit ABIN8119984

Cet anticorps anti-Bestrophin 1 Polyclonal Lapin (ABIN8119984) détecte spécifiquement Bestrophin 1 dans WB, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Bestrophin 1 anticorps (AA 161-211) (ABIN8119984)

Antigène: Bestrophin 1 (BEST1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Bestrophin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Bestrophin 1 anticorps

Épitope: AA 161-211

Fonction: Bestrophin-1 Antibody

Specificité: The antibody detects endogenous Bestrophin-1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthetic Peptide of Bestrophin-1 AA range: 161-211

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Bestrophin 1

Antigène: Bestrophin 1 (BEST1)

Autre désignation: Bestrophin-1

Sujet:

Synonyms: Bestrophin-1 (TU15B, Vitelliform macular dystrophy protein 2)

Background: This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008],

Gene Name: BEST1

Protein Name: Bestrophin-1 (TU15B) (Vitelliform macular dystrophy protein 2)

ID gène: 7439

UniProt: O76090