DC-SIGN/CD209 anticorps (AA 261-310)

N° du produit ABIN8120331

L’anticorps anti-DC-SIGN/CD209 Polyclonal Lapin est utilisé pour la détection de DC-SIGN/CD209 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour DC-SIGN/CD209 anticorps (AA 261-310) (ABIN8120331)

Antigène: DC-SIGN/CD209 (CD209) (CD209)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DC-SIGN/CD209 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-DC-SIGN/CD209 anticorps

Épitope: AA 261-310

Fonction: CD209 Antibody

Specificité: CD209 Polyclonal Antibody detects endogenous levels of CD209 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from CD209 antigen at AA range: 261-310

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur DC-SIGN/CD209

Antigène: DC-SIGN/CD209 (CD209) (CD209)

Autre désignation: CD209

Sujet:

Synonyms: CD209, CLEC4L, CD209 antigen, C-type lectin domain family 4 member L, Dendritic cell-specific ICAM-3-grabbing non-integrin 1, DC-SIGN, DC-SIGN1, CD209

Background: This gene encodes a transmembrane receptor and is often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino a

Gene Name: CD209

Protein Name: CD209 antigen

ID gène: 30835

UniProt: Q9NNX6