CENPM anticorps (AA 30-110)

N° du produit ABIN8120458

Cet anticorps anti-CENPM Polyclonal Lapin (ABIN8120458) détecte spécifiquement CENPM dans WB, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CENPM anticorps (AA 30-110) (ABIN8120458)

Antigène: CENPM (Centromere Protein M (CENPM))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CENPM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-CENPM anticorps

Épitope: AA 30-110

Fonction: CENP-M Antibody

Specificité: This antibody detects endogenous levels of human CENP-M

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human CENP-M AA range: 30-110

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-200, WB 1:500-2000. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CENPM

Antigène: CENPM (Centromere Protein M (CENPM))

Autre désignation: CENP-M

Sujet:

Synonyms: Centromere protein M (CENP-M, Interphase centromere complex protein 39, Proliferation-associated nuclear element protein 1)

Background: The protein encoded by this gene is an inner protein of the kinetochore, the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division. It belongs to the constitutive centromere-associated network protein group, whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle. The protein is structurally related to GTPases but cannot bind guanosine triphosphate. A point mutation that affects interaction with another constitutive centromere-associated network protein, CENP-I, impairs kinetochore assembly and chromosome alignment, suggesting that it is required for kinetochore formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],

Gene Name: CENPM C22orf18 ICEN39 PANE1

Protein Name: CENP-M

ID gène: 79019

UniProt: Q9NSP4