CHRNA4 anticorps (AA 300-380)

N° du produit ABIN8120527

Cet anticorps anti-CHRNA4 Polyclonal Lapin (ABIN8120527) détecte spécifiquement CHRNA4 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CHRNA4 anticorps (AA 300-380) (ABIN8120527)

Antigène: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRNA4 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CHRNA4 anticorps

Épitope: AA 300-380

Fonction: ACHA4 Antibody

Specificité: ACHA4 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human protein . at AA range: 300-380

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CHRNA4

Antigène: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Autre désignation: ACHA4

Sujet:

Background: This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012],

Gene Name: CHRNA4 NACRA4

Protein Name: Neuronal acetylcholine receptor subunit alpha-4

ID gène: 1137

UniProt: P43681

Pathways: Synaptic Membrane