Claudin 18 anticorps (AA 150-261)

N° du produit ABIN8120594

Cet anticorps Lapin Monoclonal détecte spécifiquement Claudin 18 dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Claudin 18 anticorps (AA 150-261) (ABIN8120594)

Antigène: Claudin 18 (CLDN18)

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Claudin 18 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: AB1342

Détail du produit anti-Claudin 18 anticorps

Épitope: AA 150-261

Fonction: Claudin 18 Rabbit mAb (Ready to Use)

Specificité: The antibody can specifically recognize both human Claudin 18. 1 and Claudin 18. 2 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: A synthetic peptide corresponding to the amino acid region 150 - 261 of the human Claudin 18 protein.

Isotype: IgG

Information d'application

Indications d'application: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze

Stock: 4 °C

Stockage commentaire: Store at 4°C. Avoid freeze.

Détails sur Claudin 18

Antigène: Claudin 18 (CLDN18)

Autre désignation: Claudin 18

Sujet:

Synonyms: Claudin 18,Claudin-18,CLD18_HUMAN,CLDN18,SFTA5,SFTPJ

Background: Claudin 18 is a 27 kDa membrane protein, belonging to the tight junction protein family. It is highly specifically expressed in gastric epithelial cells, and almost not expressed in other normal tissues. Studies have shown that the expression of gastric tissue increases after cancer, and the abnormal expression in pancreatic cancer, lung cancer, esophageal cancer and ovarian cancer promotes the metastasis of cancer cells. Therefore, antibody based drugs against Claudin 18 can significantly improve the survival rate of patients.

Gene Name: CLDN18

Protein Name: Claudin 18

ID gène: 51208

UniProt: P56856

Pathways: Cell-Cell Junction Organization, Hepatitis C