Coagulation Factor X anticorps (Cleaved-Arg179, Light Chain)
Aperçu rapide pour Coagulation Factor X anticorps (Cleaved-Arg179, Light Chain) (ABIN8120642)
Antigène
Voir toutes Coagulation Factor X (F10) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Cleaved-Arg179, Light Chain
-
Fonction
- FA10 (light chain, Cleaved-Arg179) Antibody
-
Specificité
- This antibody detects endogenous levels of Human FA10 (light chain, Cleaved-Arg179, protein was cleaved amino acid sequence between )
-
Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-
Immunogène
- Synthesized peptide derived from human FA10 (light chain, Cleaved-Arg179)
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB 1:1000-2000 ELISA 1:5000-20000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C/1 year
-
Date de péremption
- 12 months
-
-
- Coagulation Factor X (F10)
-
Autre désignation
- FA10
-
Sujet
-
Synonyms: Coagulation factor X (EC 3.4.21.6, Stuart factor, Stuart-Prower factor) [Cleaved into: Factor X light chain, Factor X heavy chain, Activated factor Xa heavy chain]
Background: catalytic activity:Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin.,function:Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.,online information:Factor X entry,PTM:N- and O-glycosylated.,PTM:The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway).,PTM:The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.,PTM:The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 Gla (gamma-carboxy-glutamate) domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 2 EGF-like domains.,subunit:The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds.,tissue specificity:Plasma, synthesized in the liver.,
Gene Name: F10
Protein Name: FA10 (light chain, Cleaved-Arg179)
-
ID gène
- 2159
-
UniProt
- P00742
Antigène
-