Collagen Type I anticorps

N° du produit ABIN8120670

L’anticorps anti-Collagen Type I Polyclonal Lapin est utilisé pour la détection de Collagen Type I dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour Collagen Type I anticorps (ABIN8120670)

Antigène: Collagen Type I (COL1) (Collagen, Type I (COL1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Collagen Type I est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Collagen Type I anticorps

Fonction: Collagen I Antibody

Specificité: This antibody detects endogenous levels of Collagen I.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human Collagen I Polyclonal

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000, ELISA 1:10000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Collagen Type I

Antigène: Collagen Type I (COL1) (Collagen, Type I (COL1))

Autre désignation: Collagen I

Sujet:

Synonyms: Collagen alpha-2(I) chain (Alpha-2 type I collagen)

Background: This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008],

Gene Name: COL1A2

Protein Name: Collagen alpha-2(I) chain (Alpha-2 type I collagen)

ID gène: 1278

UniProt: P08123