COX2 anticorps (AA 40-120)

N° du produit ABIN8120862

L’anticorps anti-COX2 Polyclonal Lapin est utilisé pour la détection de COX2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour COX2 anticorps (AA 40-120) (ABIN8120862)

Antigène: COX2 (Cytochrome C Oxidase Subunit II (COX2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COX2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-COX2 anticorps

Épitope: AA 40-120

Fonction: MTCO2 Antibody

Specificité: COX2 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human protein . at AA range: 40-120

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur COX2

Antigène: COX2 (Cytochrome C Oxidase Subunit II (COX2))

Autre désignation: MTCO2

Sujet:

Background: cofactor:Copper A.,disease:Defects in MT-CO2 are a cause of cytochrome c oxidase deficiency (COX deficiency) [MIM:220110], also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood.,disease:Defects in MT-CO2 are associated with tumor formation.,function:Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.,similarity:Belongs to the cytochrome c oxidase subunit 2 family.,

Gene Name: MT-CO2 COII COXII MTCO2

Protein Name: Cytochrome c oxidase subunit 2 (Cytochrome c oxidase polypeptide II)

ID gène: 4513

UniProt: P00403

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation