EEA1 anticorps

N° du produit ABIN8121126

L’anticorps anti-EEA1 Monoclonal Lapin est utilisé pour la détection de EEA1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC, ELISA, IF et IP.

Aperçu rapide pour EEA1 anticorps (ABIN8121126)

Antigène: EEA1 (Early Endosome Antigen 1 (EEA1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp EEA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: AB1761

Détail du produit anti-EEA1 anticorps

Fonction: EEA1 Rabbit mAb

Specificité: This antibody detects endogenous levels of EEA1 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: Recombinant protein (or fragment).

Isotype: IgG

Information d'application

Indications d'application: WB, 1:1000-1:5000 | IHC, 1:100-1:200 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur EEA1

Antigène: EEA1 (Early Endosome Antigen 1 (EEA1))

Autre désignation: EEA1

Sujet:

Synonyms: EEA1, ZFYVE2, Early endosome antigen 1, Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2

Background: disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases. , domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate. , function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. , similarity:Contains 1 C2H2-type zinc finger. , similarity:Contains 1 FYVE-type zinc finger. , subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding. ,

Gene Name: EEA1

Protein Name: EEA1

ID gène: 8411

UniProt: Q15075

Pathways: Toll-Like Receptors Cascades