EIF6 anticorps (pSer235)

N° du produit ABIN8121324

L’anticorps anti-EIF6 Polyclonal Lapin est utilisé pour la détection de EIF6 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour EIF6 anticorps (pSer235) (ABIN8121324)

Antigène: EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-EIF6 anticorps

Épitope: pSer235

Fonction: EIF6 (Phospho Ser235) Antibody

Specificité: This antibody detects endogenous levels of EIF6 (Phospho-Ser235) at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human EIF6 (Phospho-Ser235)

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur EIF6

Antigène: EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))

Autre désignation: EIF6

Sujet:

Synonyms: Eukaryotic translation initiation factor 6 (eIF-6) (B(2)GCN homolog) (B4 integrin interactor) (CAB) (p27(BBP))

Background: Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains.The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012],

Gene Name: EIF6 EIF3A ITGB4BP OK/SW-cl.27

Protein Name: EIF6 (Phospho-Ser235)

ID gène: 3692

UniProt: P56537

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly