XPO1 anticorps (acLys568)

N° du produit ABIN8121339

L’anticorps anti-XPO1 Polyclonal Lapin est utilisé pour la détection de XPO1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour XPO1 anticorps (acLys568) (ABIN8121339)

Antigène: XPO1 (Exportin 1 (XPO1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XPO1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-XPO1 anticorps

Épitope: acLys568

Fonction: CRM1 (Acetyl Lys568) Antibody

Specificité: Acetyl-CRM1 (K568) Polyclonal Antibody detects endogenous levels of CRM1 protein only when acetylation at K568.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized acetyl-peptide derived from the Internal region of human CRM1 around the acetylation site of K568.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur XPO1

Antigène: XPO1 (Exportin 1 (XPO1))

Autre désignation: CRM1

Sujet:

Synonyms: XPO1, CRM1, Exportin-1, Exp1, Chromosome region maintenance 1 protein homolog

Background: This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015],

Gene Name: XPO1

Protein Name: Exportin-1

ID gène: 7514

UniProt: O14980

Pathways: M Phase