FBXO22 anticorps (AA 182-232)

N° du produit ABIN8121356

Cet anticorps Lapin Polyclonal détecte spécifiquement FBXO22 dans WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour FBXO22 anticorps (AA 182-232) (ABIN8121356)

Antigène: FBXO22 (F-Box Protein 22 (FBXO22))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXO22 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FBXO22 anticorps

Épitope: AA 182-232

Fonction: FBX22 Antibody

Specificité: This antibody detects endogenous levels of FBX22 at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human FBX22 AA range: 182-232

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur FBXO22

Antigène: FBXO22 (F-Box Protein 22 (FBXO22))

Autre désignation: FBX22

Sujet:

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010],

Gene Name: FBXO22 FBX22

Protein Name: FBX22

ID gène: 26263

UniProt: Q8NEZ5

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development