GRPR anticorps

N° du produit ABIN8121616

Cet anticorps anti-GRPR Polyclonal Lapin (ABIN8121616) détecte spécifiquement GRPR dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GRPR anticorps (ABIN8121616)

Antigène: GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRPR est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GRPR anticorps

Fonction: GRPR Antibody

Specificité: GRPR Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur GRPR

Antigène: GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

Autre désignation: GRPR

Sujet:

Background: Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008],

Gene Name: GRPR

Protein Name: Gastrin-releasing peptide receptor (GRP-R) (GRP-preferring bombesin receptor)

ID gène: 2925

UniProt: P30550