GLUL anticorps (AA 400-500)

N° du produit ABIN8121691

Cet anticorps anti-GLUL Monoclonal Souris (Clone AB2426) (ABIN8121691) détecte spécifiquement GLUL dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GLUL anticorps (AA 400-500) (ABIN8121691)

Antigène: GLUL (Glutamate-Ammonia Ligase (GLUL))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GLUL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: AB2426

Détail du produit anti-GLUL anticorps

Épitope: AA 400-500

Fonction: Gl Syn/Glutamine Synthetase mouse mAb

Specificité: This antibody detects endogenous levels of Gl Syn/Glutamine Synthetase protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogène: A synthetic peptide corresponding to the amino acid region 400 - 500 of the human Beta Tubulin protein.

Isotype: IgG

Information d'application

Indications d'application: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur GLUL

Antigène: GLUL (Glutamate-Ammonia Ligase (GLUL))

Autre désignation: Gl Syn/Glutamine Synthetase

Sujet:

Synonyms: GLUL,GLNS,Glutamine synthetase,GS,Glutamate decarboxylase,Glutamate-- ammonia ligase

Background: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],

Gene Name: GLUL

Protein Name: Gl Syn/Glutamine Synthetase

ID gène: 2752

UniProt: P15104

Pathways: Positive Regulation of Peptide Hormone Secretion