GCLM anticorps

N° du produit ABIN8121693

L’anticorps anti-GCLM Monoclonal Lapin est utilisé pour la détection de GCLM dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC, ELISA, IF et IP.

Aperçu rapide pour GCLM anticorps (ABIN8121693)

Antigène: GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp GCLM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: AB1661

Détail du produit anti-GCLM anticorps

Fonction: GCLM Rabbit mAb

Specificité: This antibody detects endogenous levels of GCLM protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: Recombinant protein (or fragment).

Isotype: IgG

Information d'application

Indications d'application: WB, 1:1000-1:5000 | IHC, 1:200-1:500 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur GCLM

Antigène: GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Autre désignation: GCLM

Sujet:

Synonyms: GCLM, GLCLR, Glutamate-- cysteine ligase regulatory subunit, GCS light chain, Gamma-ECS regulatory subunit, Gamma-glutamylcysteine synthetase regulatory subunit, Glutamate-- cysteine ligase modifier subunit

Background: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],

Gene Name: GCLM

Protein Name: GCLM

ID gène: 2730

UniProt: P48507