GLN1 anticorps

N° du produit ABIN8121699

L’anticorps anti-GLN1 Monoclonal Lapin est utilisé pour la détection de GLN1 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, IHC, IF, IP et ELISA.

Aperçu rapide pour GLN1 anticorps (ABIN8121699)

Antigène: GLN1 (Glutamine Synthetase (GLN1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp GLN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA

Clone: AB1655

Détail du produit anti-GLN1 anticorps

Fonction: Glutamine Synthetase Rabbit mAb

Specificité: This antibody detects endogenous levels of Glutamine Synthetase protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: Recombinant protein (or fragment).

Isotype: IgG

Information d'application

Indications d'application: WB, 1:1000-1:5000 | IHC, 1:1000-1:4000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur GLN1

Antigène: GLN1 (Glutamine Synthetase (GLN1))

Autre désignation: Glutamine Synthetase

Sujet:

Synonyms: GLUL, GLNS, Glutamine synthetase, GS, Glutamate decarboxylase, Glutamate-- ammonia ligase

Background: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],

Gene Name: >>Arginine biosynthesis, >>Alanine, aspartate and glutamate metabolism, >>Glyoxylate and dicarboxylate metabolism, >>Nitrogen metabolism, >>Metabolic pathways, >>Biosynthesis of amino acids, >>Necroptosis, >>Glutamatergic synapse, >>GABAergic synapse

Protein Name: Glutamine Synthetase

ID gène: 2752

UniProt: P15104

Pathways: Positive Regulation of Peptide Hormone Secretion