Glutaredoxin 1 anticorps (AA 8-58)

N° du produit ABIN8121705

L’anticorps anti-Glutaredoxin 1 Polyclonal Lapin est utilisé pour la détection de Glutaredoxin 1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour Glutaredoxin 1 anticorps (AA 8-58) (ABIN8121705)

Antigène: Glutaredoxin 1 (GRX1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutaredoxin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Glutaredoxin 1 anticorps

Épitope: AA 8-58

Fonction: Glutaredoxin-1 Antibody

Specificité: This antibody detects endogenous levels of human Glutaredoxin-1

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human Glutaredoxin-1 AA range: 8-58

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Glutaredoxin 1

Antigène: Glutaredoxin 1 (GRX1)

Autre désignation: Glutaredoxin-1

Sujet:

Synonyms: Glutaredoxin-1 (Thioltransferase-1; TTase-1)

Background: This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011],

Gene Name: GLRX GRX

Protein Name: Glutaredoxin-1

ID gène: 2745

UniProt: P35754

Pathways: Cell RedoxHomeostasis