GSTM3 anticorps (AA 1-51)

N° du produit ABIN8121721

Cet anticorps anti-GSTM3 Polyclonal Lapin (ABIN8121721) détecte spécifiquement GSTM3 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GSTM3 anticorps (AA 1-51) (ABIN8121721)

Antigène: GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTM3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GSTM3 anticorps

Épitope: AA 1-51

Fonction: GSTM3 Antibody

Specificité: This antibody detects endogenous levels of GSTM3 at Human

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human GSTM3 AA range: 1-51

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur GSTM3

Antigène: GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))

Autre désignation: GSTM3

Sujet:

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008],

Gene Name: GSTM3 GST5

Protein Name: GSTM3

ID gène: 2947

UniProt: P21266