HSPB8 anticorps

N° du produit ABIN8121889

Cet anticorps anti-HSPB8 Polyclonal Lapin (ABIN8121889) détecte spécifiquement HSPB8 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour HSPB8 anticorps (ABIN8121889)

Antigène: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSPB8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HSPB8 anticorps

Fonction: Crystallin-αC Antibody

Specificité: The antibody detects endogenous Crystallin-αC protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Recombinant Protein of Crystallin-alphaC

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur HSPB8

Antigène: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Autre désignation: Crystallin-alphaC

Sujet:

Synonyms: HSPB8, CRYAC, E2IG1, HSP22, PP1629, Heat shock protein beta-8, HspB8, Alpha-crystallin C chain, E2-induced gene 1 protein, Protein kinase H11, Small stress protein-like protein HSP22

Background: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008],

Gene Name: HSPB8

Protein Name: Heat shock protein beta-8

ID gène: 26353

UniProt: Q9UJY1