HUS1 anticorps (AA 160-240)

N° du produit ABIN8122116

L’anticorps anti-HUS1 Polyclonal Lapin est utilisé pour la détection de HUS1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour HUS1 anticorps (AA 160-240) (ABIN8122116)

Antigène: HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HUS1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-HUS1 anticorps

Épitope: AA 160-240

Fonction: HUS1 Antibody

Specificité: HUS1 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human protein . at AA range: 160-240

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur HUS1

Antigène: HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))

Autre désignation: HUS1

Sujet:

Background: The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011],

Gene Name: HUS1

Protein Name: Checkpoint protein HUS1 (hHUS1)

ID gène: 3364

UniProt: O60921