ISR-beta anticorps (pTyr1345)

N° du produit ABIN8122222

Cet anticorps anti-ISR-beta Polyclonal Lapin (ABIN8122222) détecte spécifiquement ISR-beta dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ISR-beta anticorps (pTyr1345) (ABIN8122222)

Antigène: ISR-beta (Insulin Receptor beta (ISR-beta))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ISR-beta est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ISR-beta anticorps

Épitope: pTyr1345

Fonction: Insulin Receptor β (Phospho Tyr1345) Antibody

Specificité: This antibody detects endogenous levels of Human Insulin Receptor β (phospho-Tyr1345)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized phosho peptide around human Insulin Receptor beta (Tyr1345)

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur ISR-beta

Antigène: ISR-beta (Insulin Receptor beta (ISR-beta))

Autre désignation: Insulin Receptor beta

Sujet:

Synonyms: Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha, Insulin receptor subunit beta]

Background: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

Gene Name: INSR

Protein Name: Insulin Receptor β (Tyr1345)

ID gène: 3643

UniProt: P06213