ISR-beta anticorps

N° du produit ABIN8122223

Cet anticorps Lapin Monoclonal détecte spécifiquement ISR-beta dans WB, IP, ELISA, IHC et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ISR-beta anticorps (ABIN8122223)

Antigène: ISR-beta (Insulin Receptor beta (ISR-beta))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ISR-beta est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: AB2151

Détail du produit anti-ISR-beta anticorps

Fonction: Insulin Receptor β Rabbit mAb

Specificité: This antibody detects endogenous levels of Insulin Receptor β protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: Recombinant protein (or fragment).

Isotype: IgG

Information d'application

Indications d'application: WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur ISR-beta

Antigène: ISR-beta (Insulin Receptor beta (ISR-beta))

Autre désignation: Insulin Receptor beta

Sujet:

Synonyms: Insulin receptor, IR, CD antigen CD220, [Cleaved into: Insulin receptor subunit alpha, Insulin receptor subunit beta]

Background: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

Gene Name: INSR

Protein Name: Insulin Receptor β

ID gène: 3643

UniProt: P06213