CD51 anticorps (Cleaved-Asp891, Light Chain)

N° du produit ABIN8122252

Cet anticorps anti-CD51 Polyclonal Lapin (ABIN8122252) détecte spécifiquement CD51 dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour CD51 anticorps (Cleaved-Asp891, Light Chain) (ABIN8122252)

Antigène: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD51 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-CD51 anticorps

Épitope: Cleaved-Asp891, Light Chain

Fonction: ITGAV (light chain, Cleaved-Asp891) Antibody

Specificité: This antibody detects endogenous levels of Human,Mouse ITGAV (light chain, Cleaved-Asp891, protein was cleaved amino acid sequence between 890-891 )

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human ITGAV (light chain, Cleaved-Asp891)

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CD51

Antigène: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Autre désignation: ITGAV

Sujet:

Synonyms: Integrin alpha-V (Vitronectin receptor subunit alpha, CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain, Integrin alpha-V light chain]

Background: integrin subunit alpha V(ITGAV) Homo sapiens The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015],

Gene Name: ITGAV MSK8 VNRA

Protein Name: ITGAV (light chain, Cleaved-Asp891)

ID gène: 3685

UniProt: P06756

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex