IRF4 anticorps (AA 350-451)

N° du produit ABIN8122290

L’anticorps anti-IRF4 Monoclonal Lapin est utilisé pour la détection de IRF4 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour IRF4 anticorps (AA 350-451) (ABIN8122290)

Antigène: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp IRF4 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: AB1389

Détail du produit anti-IRF4 anticorps

Épitope: AA 350-451

Fonction: IRF-4/MUM1 Rabbit mAb (Ready to Use)

Specificité: The antibody can specifically recognize human MUM1 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: A synthetic peptide corresponding to the amino acid region 350 - 451 of the human IRF - 4/MUM1 protein.

Isotype: IgG

Information d'application

Indications d'application: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze

Stock: 4 °C

Stockage commentaire: Store at 4°C. Avoid freeze.

Détails sur IRF4

Antigène: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Autre désignation: IRF-4/MUM1

Sujet:

Synonyms: Interferon regulatory factor 4,IRF 4,IRF-4,Irf4,IRF4_HUMAN,LSIRF,Lymphocyte specific interferon regulatory factor,Lymphocyte specific IRF,Lymphocyte-specific interferon regulatory factor,Multiple myeloma oncogene 1,MUM 1,MUM1,NF EM5,NF-EM5,NFEM5,PU. 1 interaction partner,Sfpi1/PU. 1 interaction partner,Transcriptional activator PIP

Background: MUM1, also known as interferon regulatory factor 4, with a molecular weight of 50 kDa, is a nuclear transcription factor necessary for the development and activation of B lymphocytes. It can regulate the proliferation and differentiation of B cells and activate T lymphocytes. It is mainly used for the study of B- cell lymphoma. It is expressed in multiple myeloma, lymphoplasmacytic lymphoma and diffuse large B- cell lymphoma. It can be used as a tissue derived immunophenotypic marker of B- cell lymphoma. At the same time, it is also expressed in RS cells in anaplastic large cell lymphoma, peripheral T- cell lymphoma and classical Hodgkin's lymphoma. It is an immunophenotypic marker of malignant lymphoma, only limited to lymphocytes and melanocytes.

Gene Name: IRF4

Protein Name: MUM1

ID gène: 3662

UniProt: Q15306

Pathways: Chromatin Binding