KNG1 anticorps

N° du produit ABIN8122565

Cet anticorps Lapin Polyclonal détecte spécifiquement KNG1 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour KNG1 anticorps (ABIN8122565)

Antigène: KNG1 (Kininogen 1 (KNG1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KNG1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-KNG1 anticorps

Fonction: Kininogen 1 Antibody

Specificité: This antibody detects endogenous levels of human Kininogen 1

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Recombinant Protein derived from human Kininogen 1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-200, WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur KNG1

Antigène: KNG1 (Kininogen 1 (KNG1))

Autre désignation: Kininogen 1

Sujet:

Synonyms: Kininogen-1 (Alpha-2-thiol proteinase inhibitor) (Fitzgerald factor) (High molecular weight kininogen) (HMWK) (Williams-Fitzgerald-Flaujeac factor) [Cleaved into: Kininogen-1 heavy chain, T-kinin (Ile-Ser-Bradykinin), Bradykinin (Kallidin I), Lysyl-bradykinin (Kallidin II), Kininogen-1 light chain, Low molecular weight growth-promoting factor]

Background: This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2014],

Gene Name: KNG1 BDK KNG

Protein Name: Kininogen 1

ID gène: 3827

UniProt: P01042

Pathways: ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process