LRWD1 anticorps (AA 395-445)

N° du produit ABIN8122629

L’anticorps anti-LRWD1 Polyclonal Lapin est utilisé pour la détection de LRWD1 dans des échantillons de Humain et Souris. Il a été validé pour WB et IHC.

Aperçu rapide pour LRWD1 anticorps (AA 395-445) (ABIN8122629)

Antigène: LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRWD1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-LRWD1 anticorps

Épitope: AA 395-445

Fonction: LRWD1 Antibody

Specificité: This antibody detects endogenous levels of LRWD1 at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human LRWD1 AA range: 395-445

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur LRWD1

Antigène: LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))

Autre désignation: LRWD1

Sujet:

Background: The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],

Gene Name: LRWD1 ORCA

Protein Name: LRWD1

ID gène: 222229

UniProt: Q9UFC0

Pathways: Chromatin Binding