LIM Domain Binding 3 Protein anticorps (AA 41-90)
Aperçu rapide pour LIM Domain Binding 3 Protein anticorps (AA 41-90) (ABIN8122644)
Antigène
Voir toutes LIM Domain Binding 3 Protein (LDB3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 41-90
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Fonction
- LDB3 Antibody
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Specificité
- LDB3 Polyclonal Antibody detects endogenous levels of protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from human protein . at AA range: 41-90
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Isotype
- IgG
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Indications d'application
- WB 1:500-2000 ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))
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Autre désignation
- LDB3
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Sujet
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Background: This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins.The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified, all isoforms have N-terminal PDZ domains while only longer isoforms (
Gene Name: LDB3 KIAA0613 ZASP
Protein Name: LIM domain-binding protein 3 (Protein cypher) (Z-band alternatively spliced PDZ-motif protein)
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ID gène
- 11155
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UniProt
- O75112
Antigène
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