LRP1 anticorps

N° du produit ABIN8122676

Cet anticorps Lapin Monoclonal détecte spécifiquement LRP1 dans WB, IHC, ELISA, IP et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour LRP1 anticorps (ABIN8122676)

Antigène: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp LRP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: AB1790

Détail du produit anti-LRP1 anticorps

Fonction: LRP1 Rabbit mAb

Specificité: This antibody detects endogenous levels of LRP1 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: Recombinant protein (or fragment).

Isotype: IgG

Information d'application

Indications d'application: WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur LRP1

Antigène: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Autre désignation: LRP1

Sujet:

Synonyms: LRP1, A2MR, APR, Prolow-density lipoprotein receptor-related protein 1, LRP-1, Alpha-2-macroglobulin receptor, A2MR, Apolipoprotein E receptor, APOER, CD antigen CD91

Background: This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712) . This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer&apos, s disease patients. [provided by RefSeq, Oct 2015],

Gene Name: LRP1

Protein Name: LRP1

ID gène: 4035

UniProt: Q07954

Pathways: Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling