MED27 anticorps (AA 90-170)

N° du produit ABIN8122824

L’anticorps anti-MED27 Polyclonal Lapin est utilisé pour la détection de MED27 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour MED27 anticorps (AA 90-170) (ABIN8122824)

Antigène: MED27 (Mediator Complex Subunit 27 (MED27))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED27 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MED27 anticorps

Épitope: AA 90-170

Fonction: CRSP34 Antibody

Specificité: CRSP34 Polyclonal Antibody detects endogenous levels of CRSP34 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from CRSP34 . at AA range: 90-170

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MED27

Antigène: MED27 (Mediator Complex Subunit 27 (MED27))

Autre désignation: CRSP34

Sujet:

Synonyms: MED27, CRSP34, CRSP8, Mediator of RNA polymerase II transcription subunit 27, Cofactor required for Sp1 transcriptional activation subunit 8, CRSP complex subunit 8, Mediator complex subunit 27, P37 TRAP/SMCC/PC2 subunit, Transcriptional co

Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus.The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011],

Gene Name: MED27

Protein Name: Mediator of RNA polymerase II transcription subunit 27

ID gène: 9442

UniProt: Q6P2C8

Pathways: Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha