MFN2 anticorps

N° du produit ABIN8122981

Cet anticorps anti-MFN2 Monoclonal Lapin (Clone AB2008) (ABIN8122981) détecte spécifiquement MFN2 dans WB, IHC, ELISA, IF et IP. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour MFN2 anticorps (ABIN8122981)

Antigène: MFN2 (Mitofusin 2 (MFN2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MFN2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: AB2008

Détail du produit anti-MFN2 anticorps

Fonction: Mitofusin-2 Rabbit mAb

Specificité: This antibody detects endogenous levels of Mitofusin-2 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: Recombinant protein (or fragment).

Isotype: IgG

Information d'application

Indications d'application: WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur MFN2

Antigène: MFN2 (Mitofusin 2 (MFN2))

Autre désignation: Mitofusin-2

Sujet:

Synonyms: MFN2, CPRP1, KIAA0214, Mitofusin-2, Transmembrane GTPase MFN2

Background: This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008],

Gene Name: MFN2

Protein Name: Mitofusin-2

ID gène: 9927

UniProt: O95140

Pathways: Skeletal Muscle Fiber Development