ZAK anticorps (pSer165)

N° du produit ABIN8123024

Cet anticorps Lapin Polyclonal détecte spécifiquement ZAK dans WB. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ZAK anticorps (pSer165) (ABIN8123024)

Antigène: ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZAK est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ZAK anticorps

Épitope: pSer165

Fonction: ZAK (Phospho Ser165) Antibody

Specificité: This antibody detects endogenous levels of ZAK (Phospho-Ser165) at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human ZAK (Phospho-Ser165)

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur ZAK

Antigène: ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))

Autre désignation: ZAK

Sujet:

Synonyms: Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)

Background: This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

Gene Name: MLTK ZAK HCCS4

Protein Name: ZAK (Phospho-Ser165)

ID gène: 51776

UniProt: Q9NYL2