MPZ anticorps (AA 50-130)

N° du produit ABIN8123104

Cet anticorps anti-MPZ Polyclonal Lapin (ABIN8123104) détecte spécifiquement MPZ dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour MPZ anticorps (AA 50-130) (ABIN8123104)

Antigène: MPZ (Myelin Protein Zero (MPZ))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MPZ est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MPZ anticorps

Épitope: AA 50-130

Fonction: MYP0 Antibody

Specificité: MYP0 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human protein . at AA range: 50-130

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MPZ

Antigène: MPZ (Myelin Protein Zero (MPZ))

Autre désignation: MYP0

Sujet:

Background: This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath. The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain, which are essential for the formation and stabilization of the multilamellar structure of the compact myelin. Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies, such as Dejerine-Sottas syndrome (DSS) and congenital hypomyelinating neuropathy (CHN). A recent study showed that two isoforms are produced from the same mRNA by use of alternative in-frame translation termination codons via a stop codon readthrough mechanism. [provided by RefSeq, Oct 2015],

Gene Name: MPZ

Protein Name: Myelin protein P0 (Myelin peripheral protein) (MPP) (Myelin protein zero)

ID gène: 4359

UniProt: P25189