Myoferlin anticorps (AA 868-918)
Aperçu rapide pour Myoferlin anticorps (AA 868-918) (ABIN8123129)
Antigène
Voir toutes Myoferlin (MYOF) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 868-918
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Fonction
- MYOF Antibody
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Specificité
- This antibody detects endogenous levels of MYOF at Human/Mouse
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from human MYOF AA range: 868-918
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Isotype
- IgG
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Indications d'application
- WB 1:500-2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- Myoferlin (MYOF)
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Autre désignation
- MYOF
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Sujet
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Background: Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles.The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined. [provided by RefSeq, Dec 2008],
Gene Name: MYOF FER1L3 KIAA1207
Protein Name: MYOF
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ID gène
- 26509
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UniProt
- Q9NZM1
Antigène
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