NTAN1 anticorps (AA 83-133)
Aperçu rapide pour NTAN1 anticorps (AA 83-133) (ABIN8123212)
Antigène
Voir toutes NTAN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 83-133
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Fonction
- NTAN1 Antibody
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Specificité
- This antibody detects endogenous levels of NTAN1 at Human/Mouse
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from human NTAN1 AA range: 83-133
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Isotype
- IgG
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Indications d'application
- WB 1:500-2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- NTAN1 (N-terminal Asparagine Amidase (NTAN1))
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Autre désignation
- NTAN1
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Sujet
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Background: The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012],
Gene Name: NTAN1
Protein Name: NTAN1
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ID gène
- 123803
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UniProt
- Q96AB6
Antigène
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