NDUFA1 anticorps
Aperçu rapide pour NDUFA1 anticorps (ABIN8123219)
Antigène
Voir toutes NDUFA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- NDUFA1 Rabbit mAb
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Specificité
- This antibody detects endogenous levels of NDUFA1 protein.
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Purification
- The antibody was purified by protein A affinity chromatography.
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Immunogène
- Recombinant protein (or fragment).
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Isotype
- IgG
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Indications d'application
- WB, 1:1000-1:5000 | IHC, 1:•100-1:300 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. |
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at-20°C. Avoid freeze / thaw cycles.
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- NDUFA1 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 1, 7.5kDa (NDUFA1))
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Autre désignation
- NDUFA1
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Sujet
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Synonyms: NDUFA1, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 , Complex I-MWFE, CI-MWFE, NADH-ubiquinone oxidoreductase MWFE subunit,
Background: The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the ", hydrophobic protein", (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008],
Gene Name: NDUFA1
Protein Name: NDUFA1
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ID gène
- 4694
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UniProt
- O15239
Antigène
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