NPHP1 anticorps (AA 510-590)

N° du produit ABIN8123264

Cet anticorps Lapin Polyclonal détecte spécifiquement NPHP1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour NPHP1 anticorps (AA 510-590) (ABIN8123264)

Antigène: NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NPHP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NPHP1 anticorps

Épitope: AA 510-590

Fonction: NPHP1 Antibody

Specificité: NPHP1 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human protein . at AA range: 510-590

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur NPHP1

Antigène: NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))

Autre désignation: NPHP1

Sujet:

Background: This gene encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures. Mutations in this gene cause familial juvenile nephronophthisis type 1, a kidney disorder involving both tubules and glomeruli. Defects in this gene are also associated with Senior-Loken syndrome type 1, also referred to as juvenile nephronophthisis with Leber amaurosis, which is characterized by kidney and eye disease, and with Joubert syndrome type 4, which is characterized by cerebellar ataxia, oculomotor apraxia, psychomotor delay and neonatal breathing abnormalities, sometimes including retinal dystrophy and renal disease. Multiple transcript variants encoding diffe

Gene Name: NPHP1 NPH1

Protein Name: Nephrocystin-1 (Juvenile nephronophthisis 1 protein)

ID gène: 4867

UniProt: O15259