NPHP3 anticorps (AA 1092-1142)

N° du produit ABIN8123265

L’anticorps anti-NPHP3 Polyclonal Lapin est utilisé pour la détection de NPHP3 dans des échantillons de Humain et Souris. Il a été validé pour WB.

Aperçu rapide pour NPHP3 anticorps (AA 1092-1142) (ABIN8123265)

Antigène: NPHP3 (Nephronophthisis 3 (Adolescent) (NPHP3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NPHP3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NPHP3 anticorps

Épitope: AA 1092-1142

Fonction: NPHP3 Antibody

Specificité: This antibody detects endogenous levels of NPHP3 at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human NPHP3 AA range: 1092-1142

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur NPHP3

Antigène: NPHP3 (Nephronophthisis 3 (Adolescent) (NPHP3))

Autre désignation: NPHP3

Sujet:

Background: This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin, it is required for normal ciliary development, and it functions in renal tubular development. Mutations in this gene are associated with nephronophthisis type 3, and also with renal-hepatic-pancreatic dysplasia, and Meckel syndrome type 7. Naturally occurring read-through transcripts exist between this gene and the downstream ACAD11 (acyl-CoA dehydrogenase family, member 11) gene. [provided by RefSeq, Feb 2011],

Gene Name: NPHP3 KIAA2000

Protein Name: NPHP3

ID gène: 27031

UniProt: Q7Z494

Pathways: cAMP Metabolic Process