NKX3-1 anticorps (AA 1-100)

N° du produit ABIN8123350

Cet anticorps anti-NKX3-1 Monoclonal Souris (Clone AB1400) (ABIN8123350) détecte spécifiquement NKX3-1 dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour NKX3-1 anticorps (AA 1-100) (ABIN8123350)

Antigène: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NKX3-1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: AB1400

Détail du produit anti-NKX3-1 anticorps

Épitope: AA 1-100

Fonction: NKX3.1 Mouse mAb (Ready to Use)

Specificité: The antibody can specifically recognize human NKX3. 1 protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogène: A synthetic peptide corresponding to the amino acid region 1 - 100 of the human NKX3. 1 protein.

Isotype: IgG

Information d'application

Indications d'application: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze

Stock: 4 °C

Stockage commentaire: Store at 4°C. Avoid freeze.

Détails sur NKX3-1

Antigène: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Autre désignation: NKX3.1

Sujet:

Synonyms: BAPX 2, BAPX2, Homeobox protein NK-3 homolog A, Homeobox protein Nkx 3. 1, Homeobox protein Nkx-3. 1, Homeobox protein Nkx3. 1, NK homeobox (Drosophila) family 3 A, NK homeobox family 3 A, NK homeobox, family 3, member A, NK3 homeobox 1, NK3 transcription factor homolog A, NK3 transcription factor related locus 1, NKX 3, Nkx 3. 1, NKX 3A, NKX3 1, NKX3, Nkx3-1, NKX3. 1, Nkx3. 1, Mouse, homolog of, NKX31_HUMAN, NKX3A

Background: NKX3. 1 is a nuclear transcription factor and a negative regulator of the growth of prostatic epithelial cells. Its mRNA transcription level is regulated by androgens and plays an important role in the occurrence and differentiation of prostate organs and the maintenance of the function of mature organs. NKX3. 1 has high sensitivity and specificity in benign prostatic hyperplasia and prostate cancer, and can be used as one of the specific markers to distinguish prostate cancer, benign prostatic hyperplasia and non prostate cancer. It is also expressed in mucous glands of testis, ureter and pulmonary bronchus.

Gene Name: NKX3-1

Protein Name: NKX3. 1

ID gène: 4824

UniProt: Q99801

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus