P-Cadherin anticorps

N° du produit ABIN8123547

L’anticorps anti-P-Cadherin Monoclonal Souris est utilisé pour la détection de P-Cadherin dans des échantillons de Humain. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour P-Cadherin anticorps (ABIN8123547)

Antigène: P-Cadherin (CDH3)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp P-Cadherin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: AB1019

Détail du produit anti-P-Cadherin anticorps

Fonction: P-cadherin mouse mAb

Specificité: This antibody detects endogenous levels of P-cadherin protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogène: A synthetic peptide corresponding to the amino acid region 450-550 of the human P-cadherin protein.

Isotype: IgG

Information d'application

Indications d'application: WB, 1:500-1:2000 | IHC-P, 1:50-1:200 | IF, 1:100-400 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur P-Cadherin

Antigène: P-Cadherin (CDH3)

Autre désignation: P-cadherin

Sujet:

Synonyms: Cadherin-3 (Placental cadherin) (P-cadherin)

Background: cadherin 3(CDH3) Homo sapiens This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015],

Gene Name: CADH3

Protein Name: P-cadherin

ID gène: 1001

UniProt: P22223