PDE3A anticorps (pSer312)

N° du produit ABIN8123720

Cet anticorps Lapin Polyclonal détecte spécifiquement PDE3A dans WB. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour PDE3A anticorps (pSer312) (ABIN8123720)

Antigène: PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE3A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PDE3A anticorps

Épitope: pSer312

Fonction: PDE3A (Phospho Ser312) Antibody

Specificité: This antibody detects endogenous levels of PDE3A (Phospho-Ser312) at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human PDE3A (Phospho-Ser312)

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur PDE3A

Antigène: PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))

Autre désignation: PDE3A

Sujet:

Synonyms: cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A)

Background: This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],

Gene Name: PDE3A

Protein Name: PDE3A (Phospho-Ser312)

ID gène: 5139

UniProt: Q14432

Pathways: cAMP Metabolic Process