Podoplanin anticorps (AA 23-100)

N° du produit ABIN8123830

Cet anticorps anti-Podoplanin Monoclonal Souris (Clone AB1449) (ABIN8123830) détecte spécifiquement Podoplanin dans WB, IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Podoplanin anticorps (AA 23-100) (ABIN8123830)

Antigène: Podoplanin (PDPN)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Podoplanin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: AB1449

Détail du produit anti-Podoplanin anticorps

Épitope: AA 23-100

Fonction: Podoplanin mouse mAb

Specificité: The antibody can specifically recognize human Podoplanin protein. In western blotting of U2O2 cell lysate, the antibody can label a 36 kDa band corresponding to Podoplanin.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogène: A synthetic peptide corresponding to the amino acid region 23 - 100 of the human Podoplanin protein.

Isotype: IgG

Information d'application

Indications d'application: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur Podoplanin

Antigène: Podoplanin (PDPN)

Autre désignation: Podoplanin

Sujet:

Synonyms: Aggrus, Glycoprotein 36, Gp36, PA2. 26 antigen, T1-alpha, T1A

Background: Podoplanin, also known as D2-40 or M2A, is a 38 kDa type I transmembrane mucin with multiple O-glycosylation sites. It is highly expressed in lymphatic endothelial cells, but not in blood vessels. In addition, it is also expressed in a variety of cells, such as mesothelial cells and type I alveolar epithelial cells, follicular dendritic cells, reticular cells, ovarian and testicular germ cells. Podoplanin is a very useful marker to distinguish malignant mesothelioma and adenocarcinoma, seminoma and follicular dendritic cell sarcoma. It is also the main choice to show and quantify lymphatic and intravascular tumor infiltration.

Gene Name: PDPN

Protein Name: Podoplanin

ID gène: 10630

UniProt: Q86YL7

Pathways: Dicarboxylic Acid Transport